Published: August 2022

In the early 1990s, biologist Cynthia Kenyon discovered that an alteration to a single gene of a tiny, transparent worm could double the creature’s lifespan. The discovery spawned the field of longevity research, sending scientists chasing after the biochemical secrets that long-lived species like bowhead whales and naked mole rats carry coiled within their cells.

This report first examines the science behind this nascent industry, exploring what we know about the biology of aging and the various types of interventions scientists are studying to help slow or even reverse its corrosive effects. Then, we present the leading companies in the space right now and the status of their drug development efforts. We’ll look too, at the vast array of age-related conditions that these companies are hoping to treat at their root cause. Lastly, this report considers the need for such developments. Our aim is to make the problems, stakes, and possibilities clear to everyone.

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